We detected orthopoxvirus in 28 of 125 serum samples collected during 2009 from cattle in Uruguay. Two samples were PCR-positive for vaccinia virus and had sequences similar to those for vaccinia virus associated with outbreaks in Brazil. Autochthonous circulation of vaccinia virus in Uruguay and other South American countries cannot be ruled out.
Ahead of Print -Detection of Vaccinia Virus in Dairy Cattle Serum Samples from 2009, Uruguay - Volume 22, Number 12—December 2016 - Emerging Infectious Disease journal - CDC
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