Thursday, September 17, 2015
Ahead of Print -Heartland Virus Neutralizing Antibodies in Vertebrate Wildlife, United States, 2009–2014 - Volume 21, Number 10—October 2015 - Emerging Infectious Disease journal - CDC
Since its discovery in 2009, the tickborne Heartland virus (HRTV) has caused human illness in Missouri, Oklahoma, and Tennessee USA. To better assess the geographic distribution of HRTV, we used wildlife serology as an indicator. This retrospective evaluation determined that HRTV is widespread within the central and eastern United States.
Ahead of Print -Heartland Virus Neutralizing Antibodies in Vertebrate Wildlife, United States, 2009–2014 - Volume 21, Number 10—October 2015 - Emerging Infectious Disease journal - CDC
Ahead of Print -Heartland Virus Neutralizing Antibodies in Vertebrate Wildlife, United States, 2009–2014 - Volume 21, Number 10—October 2015 - Emerging Infectious Disease journal - CDC
Friday, September 11, 2015
Ahead of Print -Electronic Public Health Registry of Extensively Drug-Resistant Organisms, Illinois, USA - Volume 21, Number 10—October 2015 - Emerging Infectious Disease journal - CDC
In response to clusters of carbapenem-resistant Enterobacteriaceae (CRE) in Illinois, USA, the Illinois Department of Public Health and the Centers for Disease Control and Prevention Chicago Prevention Epicenter launched a statewide Web-based registry designed for bidirectional data exchange among health care facilities. CRE occurrences are entered and searchable in the system, enabling interfacility communication of patient information. For rapid notification of facilities, admission feeds are automated. During the first 12 months of implementation (November 1, 2013–October 31, 2014), 1,557 CRE reports (≈4.3/day) were submitted from 115 acute care hospitals, 5 long-term acute care hospitals, 46 long-term care facilities, and 7 reference laboratories. Guided by a state and local public health task force of infection prevention specialists and microbiologists and a nonprofit informatics entity, Illinois Department of Public Health deployed a statewide registry of extensively drug-resistant organisms. The legal, technical, and collaborative underpinnings of the system enable rapid incorporation of other emerging organisms.
Ahead of Print -Electronic Public Health Registry of Extensively Drug-Resistant Organisms, Illinois, USA - Volume 21, Number 10—October 2015 - Emerging Infectious Disease journal - CDC
Ahead of Print -Electronic Public Health Registry of Extensively Drug-Resistant Organisms, Illinois, USA - Volume 21, Number 10—October 2015 - Emerging Infectious Disease journal - CDC
Tuesday, September 8, 2015
Thursday, September 3, 2015
Ahead of Print -Detection of Mixed Infections with Plasmodium spp. by PCR, India, 2014 - Volume 21, Number 10—October 2015 - Emerging Infectious Disease journal - CDC
In 8 malaria-endemic states in India, mixed Plasmodium spp. infections were detected by PCR in 17.4% (265/1,521) of blood samples that microscopy had shown to contain only P. falciparum. The quality of microscopy must be improved because use of PCR for detection of malaria parasites is limited in rural areas.
Ahead of Print -Detection of Mixed Infections with Plasmodium spp. by PCR, India, 2014 - Volume 21, Number 10—October 2015 - Emerging Infectious Disease journal - CDC
Ahead of Print -Detection of Mixed Infections with Plasmodium spp. by PCR, India, 2014 - Volume 21, Number 10—October 2015 - Emerging Infectious Disease journal - CDC
Ahead of Print -Human Infection with Ehrlichia muris–like Pathogen, United States, 2007–20131 - Volume 21, Number 10—October 2015 - Emerging Infectious Disease journal - CDC
An Ehrlichia muris–like (EML) pathogen was detected among 4 patients in Minnesota and Wisconsin during 2009. We characterized additional cases clinically and epidemiologically. During 2004–2013, blood samples from 75,077 patients from all 50 United States were tested by PCR from the groEL gene for Ehrlichia spp. and Anaplasma phagocytophilum. During 2007–2013, samples from 69 (0.1%) patients were positive for the EML pathogen; patients were from 5 states: Indiana (1), Michigan (1), Minnesota (33), North Dakota (3), and Wisconsin (31). Most (64%) patients were male; median age was 63 (range 15–94) years; and all 69 patients reported likely tick exposure in Minnesota or Wisconsin. Fever, malaise, thrombocytopenia, and lymphopenia were the most common symptoms. Sixteen (23%) patients were hospitalized (median 4 days); all recovered, and 96% received doxycycline. Infection with the EML pathogen should be considered for persons reporting tick exposure in Minnesota or Wisconsin.
Ahead of Print -Human Infection with Ehrlichia muris–like Pathogen, United States, 2007–20131 - Volume 21, Number 10—October 2015 - Emerging Infectious Disease journal - CDC
Ahead of Print -Human Infection with Ehrlichia muris–like Pathogen, United States, 2007–20131 - Volume 21, Number 10—October 2015 - Emerging Infectious Disease journal - CDC
Wednesday, September 2, 2015
Ahead of Print -Haemaphysalis longicornis Ticks as Reservoir and Vector of Severe Fever with Thrombocytopenia Syndrome Virus in China - Volume 21, Number 10—October 2015 - Emerging Infectious Disease journal - CDC
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging hemorrhagic fever in East Asia caused by SFTS virus (SFTSV), a newly discovered phlebovirus. The Haemaphysalis longicornis tick has been suspected to be the vector of SFTSV. To determine whether SFTSV can be transmitted among ticks, from ticks to animals, and from animals to ticks, we conducted transmission studies between developmental stages of H. longicornis ticks and between ticks and mice. Using reverse transcription PCR, we also analyzed the prevalence of SFTSV infection among H. longicornis ticks collected from vegetation in Shandong Province, China. Our results showed a low prevalence of SFTSV among collected ticks (0.2%, 8/3,300 ticks), and we showed that ticks fed on SFTSV-infected mice could acquire the virus and transstadially and transovarially transmit it to other developmental stages of ticks. Furthermore, SFTSV-infected ticks could transmit the virus to mice during feeding. Our findings indicate ticks could serve as a vector and reservoir of SFTSV.
Ahead of Print -Haemaphysalis longicornis Ticks as Reservoir and Vector of Severe Fever with Thrombocytopenia Syndrome Virus in China - Volume 21, Number 10—October 2015 - Emerging Infectious Disease journal - CDC
Ahead of Print -Haemaphysalis longicornis Ticks as Reservoir and Vector of Severe Fever with Thrombocytopenia Syndrome Virus in China - Volume 21, Number 10—October 2015 - Emerging Infectious Disease journal - CDC
Ahead of Print -Risk Factors for Sustained Cholera Transmission, Juba County, South Sudan, 2014 - Volume 21, Number 10—October 2015 - Emerging Infectious Disease journal - CDC
We conducted a case–control study to identify risk factors for the 2014 cholera outbreak in Juba County, South Sudan. Illness was associated with traveling or eating away from home; treating drinking water and receiving oral cholera vaccination were protective. Oral cholera vaccination should be used to complement cholera prevention efforts.
Ahead of Print -Risk Factors for Sustained Cholera Transmission, Juba County, South Sudan, 2014 - Volume 21, Number 10—October 2015 - Emerging Infectious Disease journal - CDC
Ahead of Print -Risk Factors for Sustained Cholera Transmission, Juba County, South Sudan, 2014 - Volume 21, Number 10—October 2015 - Emerging Infectious Disease journal - CDC
Ahead of Print -Ebola Virus Outbreak Investigation, Sierra Leone, September 28–November 11, 2014 - Volume 21, Number 11—November 2015 - Emerging Infectious Disease journal - CDC
During 2014–2015, an outbreak of Ebola virus disease (EVD) swept across parts of West Africa. The China Mobile Laboratory Testing Team was dispatched to support response efforts; during September 28–November 11, 2014, they conducted PCR testing on samples from 1,635 suspected EVD patients. Of those patients, 50.4% were positive, of whom 84.6% lived within a 3-km zone along main roads connecting rural towns and densely populated cities. The median time from symptom onset to testing was 5 days. At testing, 75.7% of the confirmed patients had fever, and 94.1% reported at least 1 gastrointestinal symptom; all symptoms, except rash and hemorrhage, were more frequent in confirmed than nonconfirmed patients. Virus loads were significantly higher in EVD patients with fever, diarrhea, fatigue, or headache. The case-fatality rate was lower among patients 15–44 years of age and with virus loads of <100,000 RNA copies/mL. These findings are key for optimizing EVD control and treatment measures.
Ahead of Print -Ebola Virus Outbreak Investigation, Sierra Leone, September 28–November 11, 2014 - Volume 21, Number 11—November 2015 - Emerging Infectious Disease journal - CDC
Ahead of Print -Ebola Virus Outbreak Investigation, Sierra Leone, September 28–November 11, 2014 - Volume 21, Number 11—November 2015 - Emerging Infectious Disease journal - CDC
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